Prochlorperazine (Compro) is a rectal suppository used to treat severe nausea and vomiting
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drooling
5 mg given via deep inj, may give further doses via oral admininistration, if necessary
unpleasant breath odor
QT prolongation, sudden death, cardiac arrest, and Torsades de pointes have also occurred following treatment with prochlorperazine
Prochlorperazine is used for the prevention and treatment of nausea and vomiting
Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur
By mouth
It's taken in low doses for nausea and vomiting, and dizziness or vertigo caused by inner ear problems
The adult suppository dose is typically 25 mg for an acute migraine attack, and the maximum recommended dose is twice per day
Promethazine
If QTc <480 msec and there is no history of arrhythmias or syncopes, droperidol (1
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It works by blocking the effect of a chemical in the brain called dopamine
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Prochlorperazine 5mg tablets are an antiemetic used to treat the symptoms of vertigo and dizziness
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache
How to take Prochlorperazine tablets
Ondansetron has been associated with QT interval prolongation and prochlorperazine is a phenothiazine tranquilizer and some drugs in this class have been associated with distortions of the QT interval
Serious side effects are possible while taking Phenergan or Zofran (see Warnings section)
Dosage and frequency of administration should be adjusted according to the severity of the symptoms and the response of the Effects on Lactation and Breastmilk
, alcohol, anesthetics, narcotics)
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Neuroleptics have long been associated with sudden death and are reported to cause QT prolongation and TdP at therapeutic doses or in overdose (phenothiazines, thioridazine, haloperidol, chlorpromazine, trifluoperazine, pericycline, prochlorperazine, and fluphenazine)
Because droperidol (Inapsine) has been associated with QT prolongation, 12-lead electrocardiography is recommended before treatment is initiated
INTRODUCTION Several classes of antiemetic drugs are available that antagonize the neurotransmitter receptors known to be involved in the physiology
Go to: Continuing Education Activity The heart has an electrical system that
Print Comparing Ondansetron vs Prochlorperazine Ondansetron Prochlorperazine Prescription only Ondansetron may be used for the prevention or treatment of nausea
• Caution should
Many effective drugs are available to treat or prevent PONV, however many of these drugs have the potential to prolong the QTc on the electrocardiogram (EKG)
The new information does not change any of the recommended oral
Another comparative study between droperidol (0
Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine in children 2 years of age and older or weighing 9 kilograms (kg) (20 pounds (lbs)) and over
Molecular Weight: 564
It's not a first-choice medication because it can cause serious side effects, such as extreme sleepiness, falls, and uncontrolled muscle movements
Generic versions may still be available
vomiting of blood
Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered
Prescription and OTC
drooling
5 mg given via deep inj, may give further doses via oral admininistration, if necessary
A few people who took lithium along with a drug like this one had severe side effects and lasting brain damage
Get medical help right away if you develop a fever, mental/mood changes, headache, or dizziness
It may also be used to treat dizziness associated with problems of the inner ear such as Meniere’s Syndrome
If any of these effects last or get worse, tell your doctor or pharmacist promptly
Domperidone causes QT prolongation, Prevention and treatment of nausea and vomiting
Canadian Brand Name
This medicine should not be used to treat behavioral problems in older adult patients who have dementia